University: Università degli Studi di Firenze, Italy

Main contributions:

• develop and characterize new HCN inhibitors.
• develop single myofibril techniques and study the molecular mechanism for atrial stunning.
• provide in-vitro cell models of atrial electrophysiological remodelling.

Lab web-page: http://www.pharm.unifi.it/CMpro-v-p-20.html

Contact: elisabetta.cerbai@unifi.it

Relevant Publications:

• Eisner D & Cerbai E. Beating to time: calcium clocks, voltage clocks and cardiac pacemaker activity. Am J Physiol Heart Circ Physiol 2009/296:H561-H562. 
• Ravens U & Cerbai E. Role of potassium currents in cardiac arryhthmias. Europace 2008/10 (10):1133-7. 
• Sartiani L, Suffredini S, Stillitano F, Del Lungo M, Jaconi M, Mugelli A & Cerbai E. Serotonin plays an obligatory role in cardiac differentiation. Laboratory Investigation 2009/xxx:xx-xx. 
• Sartiani L, Stillitano F, Suffredini S, Brogioni S, Monici M, Mugelli A & Cerbai E. Chronic exposure to endothelin-1 affects the molecular and functional properties of the rapid delayed rectifier current. BBRC 2009/xxx:xx-xx. 
• Stillitano F, Lonardo G, Zicha S, Varro A, Cerbai E, Mugelli A & Nattel S. Molecular Basis of Funny Current (If) in Normal and Failing Heart. J Mol Cell Cardiol 2008/45:289-299. 
• Sartiani L, Bettiol E, Stillitano F, Mugelli A, Cerbai E, Jaconi ME. Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach. Stem Cells 2007/May:1136 - 1144.  (Link)
• Piroddi N, Belus A, Scellini B, Tesi C, Giunti G, Cerbai E, Mugelli A & Poggesi C. Tension generation and relaxation in single miofibrils from huma atrial and ventricular myocardium. Pflugers Archiv European Journal of Physiology 2007/454 (1) / April:63-73.  (Link)
• Cerbai E & Mugelli A. I(f) in non-pacemaker cells: role and pharmacological implications. Pharmacol Res. 2006/May 53 (5):416-423.  (Link)